Physical integrity: the missing link in biological monitoring and TMDLs

Physical integrity: the missing link in biological monitoring and TMDLs.

The Clean Water Act mandates that the chemical, physical, and biological integrity of our nation's waters be maintained and restored. Physical integrity has often been defined as physical habitat integrity, and as such, data collected during biological monitoring programs focus primarily on habitat quality. However, we argue that channel stability is a more appropriate measure of physical integ...

Commentary: physical functioning and coronary heart disease development: is physical activity the missing link?

SF-36 is a measure of non-condition-specific health status that was originally designed to assess the patient’s subjective efficacy of interventions. Although SF-36 has been in use for nearly 20 years, its utility as a predictor for cardiovascular disease (CVD) risk has received little attention. In this issue, Myint et al. used SF-36 to assess the relationship between ‘physical functional heal...

Psychological Therapies: The Missing Link in Improving Treatment Adherence in Patients with β-thalassemia Major

Finding the missing link

The discovery of an ancient protein complex reveals the evolutionary relationships between the proteins that help to form vesicles.

The (formerly) missing link

hen endothelial cells adhere to the extracellular matrix protein fibronectin, they can proliferate in response to growth factors. Adhesion to laminin, however, brings their cell cycles to a dead stop. Why? Given that the response depends on the composition of the extracellular matrix, Filippo Giancotti and his colleagues at the Memorial Sloan-Kettering Cancer Center (New York, NY) proposed in 1...